

| HGH can help qualified patients in the following ways... | |
| • Reverses many symptoms of aging | • Reverses muscle wasting |
| • 14% Reduction in weight and body fat after six months (on average), without dieting |
• 9% increase in lean muscle after six months, without exercise |
| • Increases energy level, endurance, and exercise capacity | • Increases cardiac output and athletic performance |
| • Reduces stress and enhances immune system | • Accelerated wound healing and skin regeneration |
| • Improves memory retention and cognitive functions | • Improved recovery rate from athletic injury |
| • Improves vision | • Achieve a younger, tighter, thicker skin |
| • Improves kidney function | • Reverse osteoporosis, Improves sleep |
What are hormones?
Hormone, secretory substance carried from one gland or organ of the body via the bloodstream
to more or less specific tissues, where it exerts some influence upon the metabolism
of the target tissue. Normally, various hormones are produced and secreted by the endocrine
glands (see endocrine system), including the pituitary, thyroid, parathyroids, adrenals,
ovaries, testes, pancreatic islets, certain portions of the gastrointestinal tract, and
the placenta, among the mammalian species. As lack of any one of them may cause serious
disorders, many hormones are now produced synthetically and used in treatment where
a deficiency exists. The hormones of the anterior pituitary include thyrotropin, adrenocorticotropic
hormone, the gonadotropic hormones, and growth hormone; the posterior pituitary secretes
antidiuretic hormone, prolactin, and oxytocin. The thyroids secrete thyroxine and calcitonin,
and the parathyroids secrete parathyroid hormone. The adrenal medulla secretes epinephrine and
norepinephrine while the cortex of the same gland releases aldosterone, corticosterone,
cortisol, and cortisone. The ovaries primarily secrete estrogen and progesterone and the
testes testosterone. The adrenal cortex, ovaries, and testes in fact produce at least small
amounts of all of the steroid hormones. The islets of Langerhans in the pancreas secrete
insulin, glucagon, and somatostatin. The kidneys also produce erythropoietin, which produces
erythrocytes (red blood cells). The passage of chyme (see digestive system) from the stomach
to the duodenum causes the latter to release secretin, which stimulates the flow of pancreatic
juice. The duodenum can also be stimulated by the presence of fats in the chyme to secrete
cholecystokinin, a hormone that stimulates the gall bladder to contract and release bile.
There is evidence that the upper intestine secretes pancreatozymin, which enhances the
amount of digestive enzymes in the pancreatic juice. In addition, the pyloric region of
the stomach secretes gastrin, a hormone that increases the secretion of hydrochloric acid
into the stomach. The placenta has been shown to secrete progesterone and chorionic gonadotropin.
There is evidence that it even contains a substance similar to growth hormone. Insects
have a unique hormonal system that includes ecdysone, a steroid that influences molting
and metamorphosis, and juvenile hormone, needed for early development. Plants, too, have a
hormonal system, which includes the auxins, the gibberellins, the cytokinins, and substances
associated with the formation of flowers, tubers, bulbs, and buds. Ethylene is said
to function as a hormone in plants, acting to hasten the ripening of fruits.
Growth Hormone levels?
The hormone most often said to affect aging and promote anti-aging is growth hormone.
Growth hormone plays a pivotal but ³intermediate² role in the anti- aging process. The lack
of this hormone doesn¹t bring about aging, but rather, the hormone lies in the
middle of the aging cascade. Giving supplemental growth hormone to the aging body will restore
some lost muscle mass and redistribute fat within the body, however it will not affect
many other common aging changes, such as hair loss.
Researchers had long noticed that growth hormone hits its peak when the body goes through the rapid growth phase during adolescence. Hence the hormone¹s name. Most growth hormone secretion takes place in brief bursts called pulses that occur during the early hours of the deepest sleep. Indeed the old adage that you grow while you sleep appears to have a basis in fact.
Interestingly, growth hormone hangs around in the bloodstream for a very few minutes. However, this is long enough to stimulate its uptake into the liver, where it is converted into growth factors. Regulation of Growth Hormone is complex and comes under the control of many factors that regulate its release and function. Growth hormone declines with age in every animal species that has been tested to date. In humans, the amount of growth hormone after the age of twenty-one to thirty-one falls about 14 percent per decade, so that the total twenty-four-hour growth hormone production rate is reduced by half by the age of sixty.
Effects of Human Growth Hormone decline
The decline in human growth hormone is directly tied to the bulging, wrinkling, saggy, flabby,
draggy creatures that we all sooner or later start to see in the mirror. Those of us
with naturally lower amounts of hormone age much faster and more visibly that those
of us who by reason of genes or high exercise level maintain a higher level of secretion
for a longer period of time. The loss of the hormone with age is similar to that
seen with menopause. And it has been given a similar name, the somatopause.
What is Gene Therapy?
Gene therapy, the use of genes and the techniques of genetic engineering in the
treatment of a genetic disorder or chronic disease. There are many techniques of gene
therapy, all of them still in experimental stages. The two basic methods are called
in vivo and ex vivo gene therapy. The in vivo method inserts genetically altered
genes directly into the patient; the ex vivo method removes tissue from the patient,
extracts the cells in question, and genetically alters them before returning them to the
patient. The challenge of gene therapy lies in development of a means to deliver the
genetic material into the nuclei of the appropriate cells, so that it will be reproduced
in the normal course of cell division and have a lasting effect. One technique involves
removing cells from a patient, fortifying them with healthy copies of the defective
gene, and reinjecting them into the patient. Another involves inserting a gene into an
inactivated or nonvirulent virus and using the virus's infective capabilities to carry
the desired gene into the patient's cells. A liposome, a tiny fat-encased pouch that
can traverse cell membranes, is also sometimes used to transport a gene into a body cell.
Another approach employing liposomes, called chimeraplasty, involves the insertion of
manufactured nucleic acid molecules (chimeraplasts) instead of entire genes to correct disease-causing
gene mutations. Once inserted, the gene may produce an essential chemical that the
patient's body cannot, remove or render harmless a substance or gene causing disease,
or expose certain cells, especially cancerous cells, to attack by conventional drugs.
Gene therapy was first used in humans in 1990 to treat a child with adenosine deaminase
deficiency (ADA), a rare hereditary immune disorder (see immunity). It is hoped that
gene therapy can be used to treat cancer, genetic diseases, and AIDS, but there are
concerns that the immune system may attack cells treated by gene therapy, that the
viral vectors could mutate and become virulent, or that altered genes might be passed to
succeeding generations. In the United States, gene therapy techniques must be approved
by the federal government. The Recombinant DNA Advisory Committee of the National Institutes
of Health oversees gene therapy experiments. Like drugs, products must pass the requirements
of the Food and Drug Administration. Gene therapy is a competitive and potentially
lucrative field, and patents have been awarded for certain techniques.
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